Supporting the implementation of comprehensive HIV prevention and treatment programs to achieve and sustain epidemic control in Zimbabwe under the President's Emergency Plan for AIDS Relief (PEPFAR) | CDC RFA JG 25 0099

Opportunity Information: Apply for CDC RFA JG 25 0099

This funding opportunity (CDC RFA JG 25 0099) is a PEPFAR-supported cooperative agreement from the Centers for Disease Control and Prevention (CDC) focused on helping Zimbabwe achieve and sustain HIV epidemic control. The main purpose is to strengthen and expand comprehensive HIV prevention and treatment services in partnership with the Zimbabwe Ministry of Health and Child Care (MoHCC), with an emphasis on practical, on-the-ground service delivery improvements that keep people healthy, reduce new infections, and maintain high levels of viral suppression. The work is designed to address persistent gaps in diagnosis, treatment continuity, and service quality, especially among populations that are often harder to reach through routine facility-based care.

Funding is projected at approximately USD 10,000,000 for Year 1, contingent on available funds. Notably, the posted Year 1 award ceiling is listed as USD 0 (none), which typically signals that an upper per-award cap is not specified in the notice rather than indicating that no funding will be provided. CDC expects to make about two awards. Because this is a cooperative agreement, recipients should anticipate substantial CDC involvement beyond standard grant oversight, such as technical guidance, strategic alignment with national and PEPFAR priorities, monitoring expectations, and support for continuous quality improvement.

Programmatically, the award supports delivery of a broad package of HIV-related services and closely linked health interventions. Core HIV components include differentiated HIV prevention and testing approaches, stronger linkage to antiretroviral therapy (ART), and improved retention strategies to keep people living with HIV on effective treatment over time. Viral load monitoring is a central pillar, reflecting the goal of ensuring that people on ART achieve and sustain viral suppression, which improves individual health outcomes and reduces onward transmission. The opportunity also prioritizes advanced HIV disease (AHD) management, meaning stronger identification and clinical management for people presenting late to care or with severe immunosuppression, where mortality risk is highest.

The grant goes beyond HIV-only programming by integrating key comorbidities and related services that commonly intersect with HIV outcomes. This includes prevention and control of non-communicable diseases (NCDs), which is increasingly important as people with HIV live longer and experience chronic conditions such as hypertension, diabetes, and other long-term illnesses that can complicate HIV care. It also emphasizes TB-HIV collaboration to improve the quality and continuity of tuberculosis and HIV services, given that TB remains a major cause of illness and death among people living with HIV. In addition, the opportunity explicitly incorporates gender-based violence (GBV) response, including post-violence care, recognizing that violence and coercion can increase HIV risk, undermine treatment adherence, and create barriers to accessing health services.

Cervical cancer screening and treatment is another major focus area, particularly for people living with HIV who face higher risks of persistent HPV infection and faster progression to cervical cancer. The program aims to improve screening coverage and ensure timely treatment of pre-cancerous lesions, which is one of the most effective ways to prevent cervical cancer deaths. The opportunity also includes a clear goal to eliminate mother-to-child transmission not only of HIV, but also viral hepatitis and syphilis, signaling an integrated approach to maternal and child health services and stronger prevention, testing, and treatment across these infections in antenatal and related care settings.

Geographically, the work is concentrated in CDC-supported provinces: Mashonaland West, Mashonaland East, Mashonaland Central, Harare, and Matabeleland North. Implementation expectations emphasize scaling up differentiated service delivery models, especially community-based approaches such as community posts. These models are intended to make services more convenient and accessible for priority populations, including men, young people, and key populations, and to reduce common barriers like travel time, clinic wait times, stigma, and inflexible service hours. The opportunity also highlights engagement with faith communities and civil society organizations to strengthen health promotion, health education, demand creation, and community support for HIV services, recognizing that community institutions often play a major role in influencing health behaviors and connecting people to care.

A central thread across the opportunity is narrowing gaps among populations with elevated HIV risk or poorer outcomes. Priority groups explicitly include key populations such as female sex workers, men who have sex with men, transgender people, people in prisons, and people who inject drugs, as well as children, adolescent girls and young women, and men at high risk for HIV. The expected impact is better identification of people who do not know their status, faster and more reliable initiation of treatment for those diagnosed, higher retention on ART, and improved viral suppression rates, alongside stronger TB-HIV service integration, expanded cervical cancer prevention services, and integrated approaches that address GBV and maternal and child transmission risks.

In terms of eligibility, the opportunity is broadly open to a wide range of applicant types, including various levels of government, public and private institutions of higher education, tribal governments and organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and other unrestricted entities. The application deadline listed is February 18, 2025, and the funding is categorized under CFDA 93.067 within the health activity area, aligning it with CDC global HIV programming supported through PEPFAR.

• The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Supporting the implementation of comprehensive HIV prevention and treatment programs to achieve and sustain epidemic control in Zimbabwe under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on 2024-12-02.
• Applicants must submit their applications by 2025-02-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.

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