Programmatic Implementation and Technical Assistance (TA) for HIV/AIDS and Tuberculosis (TB) Prevention, Care, and Treatment Services throughout the Health System in South Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR) | CDC RFA GH16 1643

Opportunity Information: Apply for CDC RFA GH16 1643

This funding opportunity is a CDC cooperative agreement under PEPFAR (Funding Opportunity Number CDC RFA GH16-1643) focused on strengthening HIV/AIDS and tuberculosis (TB) prevention, care, and treatment services across South Africa's health system. The core aim is to provide programmatic implementation support and, especially, technical assistance (TA) to improve how services are delivered at both facility and community levels. In selected program areas, the award also supports differentiated service delivery (DSD), meaning more tailored service models designed to make care easier to access and more efficient for different groups of people, including those at higher risk or with greater barriers to care.

The work is targeted geographically to 27 priority districts in the Republic of South Africa that carry a particularly high burden of HIV and TB/HIV co-infection. The intent is to concentrate resources where the epidemic impact is greatest, and where improvements in case finding, treatment initiation, retention, and viral suppression can move the country closer to epidemic control. While the opportunity emphasizes TA rather than direct service delivery as the default approach, it also allows some implementation support, particularly where it is necessary to demonstrate, scale, or sustain effective models for priority and key populations.

The expected outcomes are explicitly tied to major global performance targets: helping South Africa meet the UNAIDS 90-90-90 goals for HIV (90 percent of people living with HIV diagnosed, 90 percent of those diagnosed on sustained treatment, and 90 percent of those on treatment virally suppressed) and supporting the proposed STOP TB 90-90-90 goals for TB control. In practice, this means strengthening the full cascade for both diseases: improving HIV testing strategies and linkage to care, increasing antiretroviral therapy initiation and continuity, improving viral load monitoring and suppression, and ensuring TB screening, diagnosis, and treatment are integrated effectively in HIV settings (and vice versa). Another stated outcome is improved efficiency and effectiveness of TA and DSD, suggesting a strong interest in practical, scalable approaches that improve performance without unnecessary complexity or cost.

Because this is a cooperative agreement, CDC is expected to have substantial involvement beyond standard grant oversight. That typically signals closer collaboration on technical direction, monitoring, and performance management, with a heavy emphasis on measurable results in the priority districts. The funding activity category is Health, and the CFDA number is 93.067. The opportunity anticipated up to 5 awards, with an award ceiling listed at $170,000,000, indicating a large-scale investment intended to support significant coverage across the targeted districts.

Eligibility is broad and includes a wide range of domestic and non-U.S. entities. Eligible applicants include various levels of government (state, county, city/township, special districts, U.S. territories), regional organizations, public and private institutions of higher education, independent school districts, tribal governments and tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and individuals. It also explicitly includes non-domestic (non-U.S.) entities and a variety of health and research-oriented organizations when the proposed activities are non-research in nature. Additional eligible categories listed include Ministries of Health, tribal epidemiology centers, urban Indian health organizations, colleges and universities, community-based and faith-based organizations, hospitals, and small, minority-, and women-owned businesses, along with "all other eligible organizations." This wide eligibility reflects the reality that large HIV/TB health system efforts often require partnerships that combine clinical capacity, community reach, data and quality improvement expertise, and operational management.

Key administrative details in the source information include the sponsor (Centers for Disease Control - CGH), the original closing date (2016-02-16), and the creation date of the opportunity record (2015-12-15). Overall, the opportunity is structured to accelerate HIV and TB/HIV epidemic control in South Africa by improving the performance, reach, and sustainability of prevention and treatment services, with a particular emphasis on high-burden districts and on populations that are often underserved or at highest risk.

• The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Programmatic Implementation and Technical Assistance (TA) for HIV/AIDS and Tuberculosis (TB) Prevention, Care, and Treatment Services throughout the Health System in South Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on 2015-12-15.
• Applicants must submit their applications by 2016-02-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $170,000,000.00 in funding.
• The number of recipients for this funding is limited to 5 candidate(s).
• Eligible applicants include: Others.

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