Opportunity Information: Apply for CDC RFA GH16 1643
This funding opportunity is a CDC cooperative agreement under PEPFAR (Funding Opportunity Number CDC RFA GH16-1643) focused on strengthening HIV/AIDS and tuberculosis (TB) prevention, care, and treatment services across South Africa's health system. The core aim is to provide programmatic implementation support and, especially, technical assistance (TA) to improve how services are delivered at both facility and community levels. In selected program areas, the award also supports differentiated service delivery (DSD), meaning more tailored service models designed to make care easier to access and more efficient for different groups of people, including those at higher risk or with greater barriers to care.
The work is targeted geographically to 27 priority districts in the Republic of South Africa that carry a particularly high burden of HIV and TB/HIV co-infection. The intent is to concentrate resources where the epidemic impact is greatest, and where improvements in case finding, treatment initiation, retention, and viral suppression can move the country closer to epidemic control. While the opportunity emphasizes TA rather than direct service delivery as the default approach, it also allows some implementation support, particularly where it is necessary to demonstrate, scale, or sustain effective models for priority and key populations.
The expected outcomes are explicitly tied to major global performance targets: helping South Africa meet the UNAIDS 90-90-90 goals for HIV (90 percent of people living with HIV diagnosed, 90 percent of those diagnosed on sustained treatment, and 90 percent of those on treatment virally suppressed) and supporting the proposed STOP TB 90-90-90 goals for TB control. In practice, this means strengthening the full cascade for both diseases: improving HIV testing strategies and linkage to care, increasing antiretroviral therapy initiation and continuity, improving viral load monitoring and suppression, and ensuring TB screening, diagnosis, and treatment are integrated effectively in HIV settings (and vice versa). Another stated outcome is improved efficiency and effectiveness of TA and DSD, suggesting a strong interest in practical, scalable approaches that improve performance without unnecessary complexity or cost.
Because this is a cooperative agreement, CDC is expected to have substantial involvement beyond standard grant oversight. That typically signals closer collaboration on technical direction, monitoring, and performance management, with a heavy emphasis on measurable results in the priority districts. The funding activity category is Health, and the CFDA number is 93.067. The opportunity anticipated up to 5 awards, with an award ceiling listed at $170,000,000, indicating a large-scale investment intended to support significant coverage across the targeted districts.
Eligibility is broad and includes a wide range of domestic and non-U.S. entities. Eligible applicants include various levels of government (state, county, city/township, special districts, U.S. territories), regional organizations, public and private institutions of higher education, independent school districts, tribal governments and tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and individuals. It also explicitly includes non-domestic (non-U.S.) entities and a variety of health and research-oriented organizations when the proposed activities are non-research in nature. Additional eligible categories listed include Ministries of Health, tribal epidemiology centers, urban Indian health organizations, colleges and universities, community-based and faith-based organizations, hospitals, and small, minority-, and women-owned businesses, along with "all other eligible organizations." This wide eligibility reflects the reality that large HIV/TB health system efforts often require partnerships that combine clinical capacity, community reach, data and quality improvement expertise, and operational management.
Key administrative details in the source information include the sponsor (Centers for Disease Control - CGH), the original closing date (2016-02-16), and the creation date of the opportunity record (2015-12-15). Overall, the opportunity is structured to accelerate HIV and TB/HIV epidemic control in South Africa by improving the performance, reach, and sustainability of prevention and treatment services, with a particular emphasis on high-burden districts and on populations that are often underserved or at highest risk.Apply for CDC RFA GH16 1643
- The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Programmatic Implementation and Technical Assistance (TA) for HIV/AIDS and Tuberculosis (TB) Prevention, Care, and Treatment Services throughout the Health System in South Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on 2015-12-15.
- Applicants must submit their applications by 2016-02-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $170,000,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Others.
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Frequently Asked Questions (FAQs)
1) What is the funding opportunity number for this grant?
The Funding Opportunity Number (FON) is CDC RFA GH16-1643.
2) Who is the sponsoring agency for this opportunity?
The sponsor is the Centers for Disease Control (CDC) - CGH.
3) What type of funding mechanism is this?
This opportunity is a CDC cooperative agreement under PEPFAR.
4) What does it mean that this is a cooperative agreement?
Because it is a cooperative agreement, CDC is expected to have substantial involvement beyond standard grant oversight. This typically includes closer collaboration on technical direction, monitoring, and performance management, with a strong emphasis on measurable results in the priority districts.
5) What is the main purpose of this award?
The core aim is to strengthen HIV/AIDS and tuberculosis (TB) prevention, care, and treatment services across South Africa's health system by providing programmatic implementation support and, especially, technical assistance (TA) to improve service delivery at both facility and community levels.
6) Is the award focused more on technical assistance or direct service delivery?
The opportunity emphasizes technical assistance (TA) rather than direct service delivery as the default approach. However, it allows some implementation support, particularly when needed to demonstrate, scale, or sustain effective models for priority and key populations.
7) What is meant by "technical assistance (TA)" in this opportunity?
TA refers to support aimed at improving how HIV and TB services are delivered, including collaboration on technical direction, monitoring, and performance management to strengthen results across the service cascade at facility and community levels.
8) What is differentiated service delivery (DSD), and how does it fit into this award?
Differentiated service delivery (DSD) refers to more tailored service models designed to make care easier to access and more efficient for different groups of people, including those at higher risk or with greater barriers to care. In selected program areas, the award supports DSD as part of strengthening delivery of HIV/TB services.
9) Where will the work be implemented?
The work is geographically targeted to 27 priority districts in the Republic of South Africa that have a particularly high burden of HIV and TB/HIV co-infection.
10) Why does the opportunity focus on 27 priority districts?
The intent is to concentrate resources where the epidemic impact is greatest, and where improvements in case finding, treatment initiation, retention, and viral suppression can move the country closer to epidemic control.
11) What health conditions and program areas does this funding address?
The opportunity focuses on HIV/AIDS and tuberculosis (TB), including TB/HIV co-infection, and strengthening prevention, care, and treatment services across the health system.
12) What are the expected outcomes for HIV?
Expected outcomes are tied to the UNAIDS 90-90-90 goals for HIV: 90 percent of people living with HIV diagnosed, 90 percent of those diagnosed on sustained treatment, and 90 percent of those on treatment virally suppressed.
13) What are the expected outcomes for TB?
The opportunity supports the proposed STOP TB 90-90-90 goals for TB control and emphasizes integrating TB screening, diagnosis, and treatment effectively in HIV settings (and vice versa).
14) What parts of the HIV "cascade" does the opportunity aim to strengthen?
The opportunity aims to strengthen the full HIV cascade, including improving HIV testing strategies and linkage to care, increasing antiretroviral therapy initiation and continuity, improving viral load monitoring, and increasing viral suppression.
15) How does the opportunity address integration of HIV and TB services?
It emphasizes ensuring TB screening, diagnosis, and treatment are integrated effectively in HIV settings, and that HIV services are integrated effectively in TB-related settings as appropriate.
16) What does the opportunity mean by improving the efficiency and effectiveness of TA and DSD?
One stated outcome is improved efficiency and effectiveness of TA and DSD, indicating strong interest in practical, scalable approaches that improve performance without unnecessary complexity or cost.
17) What is the funding activity category?
The funding activity category is Health.
18) What is the CFDA number for this opportunity?
The CFDA number listed is 93.067.
19) How many awards are anticipated?
The opportunity anticipated up to 5 awards.
20) What is the award ceiling?
The award ceiling is listed at $170,000,000.
21) Who is eligible to apply?
Eligibility is broad and includes a wide range of domestic and non-U.S. entities. Eligible applicants include various levels of government, regional organizations, public and private institutions of higher education, independent school districts, tribal governments and tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and individuals.
22) Are non-U.S. (non-domestic) organizations eligible to apply?
Yes. The opportunity explicitly includes non-domestic (non-U.S.) entities among eligible applicants.
23) Are for-profit organizations eligible?
Yes. For-profit organizations (including small businesses) are included in the eligibility list.
24) Are nonprofits required to have 501(c)(3) status to be eligible?
No. The eligibility list includes nonprofits with or without 501(c)(3) status.
25) Are academic institutions eligible?
Yes. Public and private institutions of higher education and colleges and universities are included among eligible applicants.
26) Are hospitals, community-based organizations, and faith-based organizations eligible?
Yes. The eligibility categories explicitly include hospitals, community-based organizations, and faith-based organizations.
27) Are Ministries of Health included as eligible applicants?
Yes. Ministries of Health are explicitly listed among eligible applicant categories.
28) Are tribal entities eligible to apply?
Yes. Tribal governments, tribal organizations, tribal epidemiology centers, and urban Indian health organizations are included in the eligibility list.
29) Does the opportunity allow health and research-oriented organizations to apply?
Yes. It includes a variety of health and research-oriented organizations when the proposed activities are non-research in nature.
30) What is the submission deadline listed for this opportunity?
The original closing date listed is 2016-02-16.
31) When was the opportunity record created?
The creation date of the opportunity record is 2015-12-15.
32) What is the overall intent of the opportunity in South Africa?
Overall, the opportunity is structured to accelerate HIV and TB/HIV epidemic control in South Africa by improving the performance, reach, and sustainability of prevention and treatment services, with an emphasis on high-burden districts and on populations that are often underserved or at highest risk.
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