Opportunity Information: Apply for RFA CE 22 010
This CDC funding opportunity (RFA CE 22 010) supports investigator-initiated research focused on preventing overdose by improving how people with illicit substance use disorders get connected to, and stay connected to, recovery support services in their own communities. The core idea is that long-term recovery often depends on more than clinical treatment alone. People benefit when they are linked to practical, ongoing supports such as peer recovery services, recovery community organizations, recovery housing, employment and job training programs, educational supports, family and relationship supports, transportation assistance, and other evidence-based services that help stabilize daily life and strengthen social supports over time.
The Notice of Funding Opportunity is specifically interested in identifying and rigorously evaluating strategies, programs, or policies that do two things: (1) link people who are in recovery to at least one evidence-based recovery support service available in their community, and (2) if someone resumes illicit substance use, re-link them back to services quickly and effectively to encourage a return to care and reduce overdose risk. The research emphasis is on strategies tailored to the individual, recognizing that people have different needs, barriers, strengths, and levels of support. The CDC highlights the concept of building "recovery capital," meaning the personal, social, and material resources that make recovery more likely to be sustained (for example, healthier relationships, safer social networks, stable housing, and access to employment opportunities).
A key term in this NOFO is "recovery ecosystem," defined as the set of recovery support services available within a community that can be tailored to an individual's needs. In practice, this can mean connecting a person to multiple coordinated services, potentially at multiple points in time, rather than a one-time referral. The CDC is looking for research that helps determine which linkage approaches are actually effective and replicable, including how to operationalize these connections in real-world systems where people may cycle in and out of care or experience setbacks.
Projects funded under this opportunity are expected to conduct both process and outcome evaluations of the linkage strategies being studied. A process evaluation would typically examine how the strategy was implemented, who it reached, the quality and fidelity of the approach, barriers and facilitators to implementation, and how well different parts of the linkage model worked together. An outcome evaluation would measure whether the strategy improves key health and recovery outcomes. The NOFO explicitly calls out outcomes such as maintaining recovery, successfully re-linking people to care after a return to use, and preventing overdose, while allowing room for other relevant measures tied to improved stability and wellbeing.
Administratively, this is a discretionary grant program run by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC). The CFDA number listed is 93.136. Eligible applicants are broad and include state, county, and local governments; tribal governments and tribal organizations; public housing authorities; K-12 independent school districts; public and private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); and other entities as allowed under the NOFO eligibility clarifications. The award ceiling is $750,000, with an expected five awards. The opportunity was created December 20, 2021, and the original application deadline was March 14, 2022 (applications due by 5:00 pm ET).
Overall, the grant is aimed at producing strong, practical evidence about what works to connect people to community-based recovery supports in a way that can be maintained over time, adapted to individual needs, and reactivated quickly when someone is at risk of falling out of recovery, with the ultimate public health goal of reducing overdose and improving long-term recovery outcomes.Apply for RFA CE 22 010
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Rigorous Evaluation of Strategies to Prevent Overdose through Linking People with Illicit Substance Use Disorders to Recovery Support Services" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
- This funding opportunity was created on Dec 20, 2021.
- Applicants must submit their applications by Mar 14, 2022 Electronically submitted applications must be submitted no later than 500 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: CDC RFA CE 22 010 (Overdose Prevention Through Recovery Support Linkage Research)
What is this funding opportunity about?
This CDC funding opportunity (RFA CE 22 010) supports investigator-initiated research focused on preventing overdose by improving how people with illicit substance use disorders get connected to, and stay connected to, recovery support services in their own communities.
What is the main public health goal of the grant?
The overarching goal is to reduce overdose risk and improve long-term recovery outcomes by generating strong, practical evidence about strategies that connect people to community-based recovery supports and keep those connections going over time, including after setbacks.
What problem is CDC trying to address with this research?
The opportunity is built on the idea that long-term recovery often depends on more than clinical treatment alone. People may need ongoing, practical supports in everyday life, and they may cycle in and out of care or experience a return to illicit substance use. CDC is looking for evidence on strategies that work in real-world systems and can be replicated.
What types of strategies is CDC specifically interested in evaluating?
The Notice of Funding Opportunity is interested in strategies, programs, or policies that do two things: (1) link people who are in recovery to at least one evidence-based recovery support service available in their community, and (2) if someone resumes illicit substance use, re-link them back to services quickly and effectively to encourage a return to care and reduce overdose risk.
Does the strategy have to include both initial linkage and re-linkage after a return to use?
Yes. The NOFO explicitly describes interest in approaches that both connect people to at least one evidence-based recovery support service and also support rapid and effective re-linkage if someone resumes illicit substance use.
What does "tailored to the individual" mean in this NOFO?
The research emphasis is on strategies tailored to the individual, recognizing that people have different needs, barriers, strengths, and levels of support. This implies linkage approaches may differ from person to person rather than relying on a single one-size-fits-all referral.
What is meant by "recovery ecosystem"?
In this NOFO, a "recovery ecosystem" is defined as the set of recovery support services available within a community that can be tailored to an individual's needs. In practice, this can mean connecting a person to multiple coordinated services, potentially at multiple points in time, rather than a one-time referral.
What is "recovery capital" and why does it matter here?
CDC highlights "recovery capital" as the personal, social, and material resources that make recovery more likely to be sustained. Examples given include healthier relationships, safer social networks, stable housing, and access to employment opportunities. The grant is aligned with building and strengthening these resources through community-based supports.
What kinds of recovery support services are referenced as examples?
The opportunity mentions practical, ongoing supports such as peer recovery services, recovery community organizations, recovery housing, employment and job training programs, educational supports, family and relationship supports, transportation assistance, and other evidence-based services that help stabilize daily life and strengthen social supports over time.
Is this grant focused on clinical treatment programs?
The core idea emphasizes that recovery often depends on more than clinical treatment alone. The focus is on connection to community-based recovery support services and maintaining or re-establishing those connections over time.
What does CDC mean by "linkage" in this context?
Linkage refers to connecting people who are in recovery to at least one evidence-based recovery support service in their community. The NOFO also stresses that linkage may involve multiple coordinated services and may occur at multiple points in time, rather than a single referral.
What does CDC mean by "re-linkage"?
Re-linkage refers to quickly and effectively connecting someone back to services if they resume illicit substance use, with the intent to encourage a return to care and reduce overdose risk.
What does the NOFO expect projects to evaluate?
Projects are expected to conduct both process and outcome evaluations of the linkage strategies being studied.
What is a process evaluation in this NOFO?
A process evaluation would typically examine how the strategy was implemented, who it reached, the quality and fidelity of the approach, barriers and facilitators to implementation, and how well different parts of the linkage model worked together.
What is an outcome evaluation in this NOFO?
An outcome evaluation would measure whether the strategy improves key health and recovery outcomes. The NOFO calls out outcomes such as maintaining recovery, successfully re-linking people to care after a return to use, and preventing overdose, while allowing room for other relevant measures tied to improved stability and wellbeing.
What outcomes does CDC explicitly mention?
The NOFO explicitly mentions maintaining recovery, successfully re-linking people to care after a return to use, and preventing overdose. It also leaves room for other measures tied to improved stability and wellbeing.
Who is administering this grant?
This is a discretionary grant program run by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC).
What is the CFDA number for this opportunity?
The CFDA number listed is 93.136.
Who is eligible to apply?
Eligible applicants are broad and include state, county, and local governments; tribal governments and tribal organizations; public housing authorities; K-12 independent school districts; public and private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); and other entities as allowed under the NOFO eligibility clarifications.
Are for-profit organizations allowed to apply?
Yes. The eligibility list includes for-profit organizations, including small businesses.
Are nonprofits required to be 501(c)(3) organizations?
No. The eligibility list includes both 501(c)(3) and non-501(c)(3) nonprofits.
How much funding is available per award?
The award ceiling is $750,000.
How many awards does CDC expect to make?
The opportunity states an expected five awards.
When was this opportunity created and when were applications due?
The opportunity was created on December 20, 2021. The original application deadline was March 14, 2022, with applications due by 5:00 pm ET.
Is this a research grant or a service delivery grant?
Based on the description, it is a research-focused grant supporting investigator-initiated research and rigorous evaluation of strategies, programs, or policies that improve linkage and re-linkage to recovery support services.
Does the NOFO require the research to be "rigorous"?
Yes. The NOFO states interest in identifying and rigorously evaluating strategies, programs, or policies that improve linkage and re-linkage to recovery support services.
What does CDC want to learn from funded projects?
CDC is looking for research that helps determine which linkage approaches are effective and replicable, including how to operationalize these connections in real-world systems where people may cycle in and out of care or experience setbacks.
Does the NOFO imply that a one-time referral is enough?
No. The description emphasizes that connecting someone to services may involve multiple coordinated services and may happen at multiple points in time, rather than being a one-time referral.
Do projects need to focus on community-based supports?
Yes. The opportunity centers on connecting people to recovery support services available in their own communities and improving how those community connections are made and maintained.
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